MonoBehaviour.OnApplicationPause(bool)
Description

Sent to all game objects when the player pauses.

OnApplicationPause can be a co-routine, simply use the yield statement in the function. If it is implemented as a coroutine, it will be evaluated twice during the initial frame: first as an early notification and second time during the normal coroutine update step.
    var paused: boolean;

function OnGUI() { // Show a message if the game is paused. if (paused) { GUI.Label(new Rect(100, 100, 50, 30), "Game paused"); } }

function OnApplicationPause(pauseStatus: boolean) { paused = pauseStatus; }