When you have an animation clips ready to use, you need to use an Animator Controller to bring them together. An Animator Controller asset is created within Unity and allows you to maintain a set of animations for a character or object. In most situations, it is normal to have multiple animations and switch between them when certain game conditions occur. For example, you could switch from a walk animation to a jump whenever the spacebar is pressed. However even if you just have a single animation clip you still need to place it into an animator controller to use it on a Game Object.
The controller manages the various animation states and the transitions between them using a so-called State Machine, which could be thought of as a kind of flow-chart, or a simple program written in a visual programming language within Unity. More information about state machines can be found here.
The animator controller is finally applied to an object by attaching an Animator component that references them. See the reference manual pages about the Animator component and Animator Controller for further details about their use.