GL.LINES

Description

Mode for Begin: draw lines.

If you want to draw something 2D in screen space then probably you will want to use GL.LoadOrtho or GL.LoadPixelMatrix.
If you want something in "3D", then probably you should consider using GL.LoadIdentity followed by GL.MultMatrix with the actual 3D transform you want your stuff to be in.

	// Draws a line from "startVertex" var to the curent mouse position.
	var mat : Material;
	private var startVertex : Vector3;
	private var mousePos : Vector3;
	startVertex = Vector3(0,0,0);
	function Update() {
		mousePos = Input.mousePosition;
		// Press space to update startVertex
		if(Input.GetKeyDown(KeyCode.Space)){
			startVertex = Vector3(mousePos.x/Screen.width, mousePos.y/Screen.height, 0);
		}
	}
	function OnPostRender() {
		if (!mat) {
			Debug.LogError("Please Assign a material on the inspector");
			return;
		}
		GL.PushMatrix();
		mat.SetPass(0);
		GL.LoadOrtho();
		GL.Begin(GL.LINES);
		GL.Color(Color.red);
		GL.Vertex(startVertex);
		GL.Vertex(Vector3(mousePos.x/Screen.width, mousePos.y/Screen.height, 0));
		GL.End();
		GL.PopMatrix();
	}

using UnityEngine;
using System.Collections;

public class ExampleClass : MonoBehaviour {
    public Material mat;
    private Vector3 startVertex;
    private Vector3 mousePos;
    void Update() {
        mousePos = Input.mousePosition;
        if (Input.GetKeyDown(KeyCode.Space))
            startVertex = new Vector3(mousePos.x / Screen.width, mousePos.y / Screen.height, 0);
        
    }
    void OnPostRender() {
        if (!mat) {
            Debug.LogError("Please Assign a material on the inspector");
            return;
        }
        GL.PushMatrix();
        mat.SetPass(0);
        GL.LoadOrtho();
        GL.Begin(GL.LINES);
        GL.Color(Color.red);
        GL.Vertex(startVertex);
        GL.Vertex(new Vector3(mousePos.x / Screen.width, mousePos.y / Screen.height, 0));
        GL.End();
        GL.PopMatrix();
    }
    void Example() {
        startVertex = new Vector3(0, 0, 0);
    }
}

import UnityEngine
import System.Collections

public class ExampleClass(MonoBehaviour):

	public mat as Material

	private startVertex as Vector3

	private mousePos as Vector3

	def Update() as void:
		mousePos = Input.mousePosition
		if Input.GetKeyDown(KeyCode.Space):
			startVertex = Vector3((mousePos.x / Screen.width), (mousePos.y / Screen.height), 0)

	def OnPostRender() as void:
		if not mat:
			Debug.LogError('Please Assign a material on the inspector')
			return
		GL.PushMatrix()
		mat.SetPass(0)
		GL.LoadOrtho()
		GL.Begin(GL.LINES)
		GL.Color(Color.red)
		GL.Vertex(startVertex)
		GL.Vertex(Vector3((mousePos.x / Screen.width), (mousePos.y / Screen.height), 0))
		GL.End()
		GL.PopMatrix()

	def Example() as void:
		startVertex = Vector3(0, 0, 0)