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CloseIndicates that Unity should perform the default checks and validation when you update a Mesh's data.
You can use this flag with "advanced" Mesh API, which includes the following methods: Mesh.SetVertexBufferData, Mesh.SetIndexBufferData, Mesh.SetSubMesh.
For information about the difference between the simpler and more advanced methods of assigning data to a Mesh from script, see the notes on the Mesh page.